Activation Mechanisms for Organometallic Anticancer Complexes
نویسندگان
چکیده
Organometallic complexes offer potential for design as anticancer drugs. They can act as inert scaffolds and specifically inhibit enzymes such as kinases, or as pro-drugs which undergo activation by various mechanisms. The activation of metallocenes, arene, alkyl or aryl complexes by hydrolysis, and metalor ligandbased redox reactions is discussed.
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تاریخ انتشار 2017